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Fréquence des polymorphismes du CYP2C9 chez les Polynésiens et pertinence potentielle concernant le traitement de la goutte par benzbromarone

Description:
La goutte est un problème de santé publique chez les Polynésiens et l’allopurinol, traitement de choix dans la goutte, semble être moins efficace chez eux. La benzbromarone, médicament uricosurique, est un traitement alternatif mais les métaboliseurs lents (ML) de CYP2C9 peuvent être à haut risque d’hépatotoxicité liée à la benzbromarone. Les objectifs de cette étude étaient de déterminer la fr...
Display date:
2014-03
Format:
Scholarly text
Collections:
Otago University Research Archive
Publisher:
Elsevier SAS
Content partner:
University of Otago
Availability:
Not specified
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