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Integrative analysis identifies two molecular and clinical subsets in Luminal B breast cancer

Description:
Comprehensive multiplatform analysis of Luminal B breast cancer (LBBC) specimens identifies two molecularly distinct, clinically relevant subtypes: Cluster A associated with cell cycle and metabolic signaling and Cluster B with predominant epithelial mesenchymal transition (EMT) and immune response pathways. Whole-exome sequencing identified significantly mutated genes including TP53, PIK3CA, E...
Display date:
2023-09-15
Format:
Journal article
Collections:
Massey Research Online
Publisher:
Elsevier Inc
Content partner:
Massey University
Availability:
Not specified
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